MyBioSource.com's Rabbit Anti-Histone H2B type 1-M Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA. The Rabbit Anti-Histone H2B type 1-M Antibody was generated using H2B clustered histone 14, and H2BC14 as the antigen and it reacts with Mouse.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling